Guidelines for using animal models in blast injury research

Author
Watts, Sarah
Kirkman, Emrys
Bieler, Dan
Bjarnason, Stephen
Franke, Axel
Gupta, Raj Kumari
Leggieri, Michael J.
Orru, Hans
Ouellet, Simon
Philippens, Mat M. G. M.
Sarron, Jean-Claude
Skriudalen, Stian
Teland, Jan Arild
Risling, Mårten
Cernak, Ibolja
Date Issued
2018
Keywords
Skuddsår
Forsøksdyr
Permalink
http://hdl.handle.net/123456789/77670
http://hdl.handle.net/20.500.12242/2510
DOI
10.1136/jramc-2018-000956
Collection
Articles
Description
Watts, Sarah; Kirkman, Emrys; Bieler, Dan; Bjarnason, Stephen; Franke, Axel; Gupta, Raj Kumari; Leggieri, Michael J.; Orru, Hans; Ouellet, Simon; Philippens, Mat M. G. M.; Sarron, Jean-Claude; Skriudalen, Stian; Teland, Jan Arild; Risling, Mårten; Cernak, Ibolja. Guidelines for using animal models in blast injury research. Journal of the Royal Army Medical Corps 2018
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Abstract
Blast injury is a very complex phenomenon and frequently results in multiple injuries. One method to investigate the consequences of blast injuries is with the use of living systems (animal models). The use of animals allows the examination and evaluation of injury mechanisms in a more controlled manner, allowing variables such as primary or secondary blast injury for example, to be isolated and manipulated as required. To ensure a degree of standardisation across the blast research community a set of guidelines which helps researchers navigate challenges of modelling blast injuries in animals is required. This paper describes the guidelines for Using Animal Models in Blast Injury Research developed by the NATO Health Factors and Medicine (HFM) Research Task Group 234.
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