Complete genome sequences of six Legionella pneumophila isolates from two collocated outbreaks of legionnaires' disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway

Author
Dybwad, Marius
Aarskaug, Tone
Fykse, Else-Marie
Madslien, Elisabeth Henie
Blatny, Janet Martha
Date Issued
2016
Keywords
Legionella
Genomanalyse
Permalink
http://hdl.handle.net/20.500.12242/610
https://ffi-publikasjoner.archive.knowledgearc.net/handle/20.500.12242/610
DOI
10.1128/genomeA.01367-16
Collection
Articles
Description
Dybwad, Marius; Aarskaug, Tone; Fykse, Else-Marie; Madslien, Elisabeth Henie; Blatny, Janet Martha. Complete genome sequences of six Legionella pneumophila isolates from two collocated outbreaks of legionnaires' disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway. Genome Announcements 2016 ;Volum 4.(6)
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Abstract
Here, we report the complete genome sequences of Legionella pneumophila isolates from two collocated outbreaks of Legionnaires’ disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway. One clinical and two environmental isolates were sequenced from each outbreak. The genome of all six isolates consisted of a 3.36 Mb-chromosome, while the 2005 genomes featured an additional 68 kb-episome sharing high sequence similarity with the L. pneumophila Lens plasmid. All six genomes contained multiple mobile genetic elements including novel combinations of type-IVA secretion systems. A comparative genomics study will be launched to resolve the genetic relationship between the L. pneumophila isolates.
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